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Mitochondrial involvement in cocaine-treated rat hepatocytes: effect of N-acetylcysteine and deferoxamine
1. The cytotoxicity of cocaine (0–1000 μM), was studied on parameters related to the mitochondrial role and the cascade of events that lead to apoptosis in hepatocyte cultures from phenobarbitone (PB) pretreated rats. 2. Cytotoxicity was dose-dependent and LDH leakage was significantly enhanced abov...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2001
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1572648/ https://ncbi.nlm.nih.gov/pubmed/11226137 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0703909 |
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