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Anandamide activates peripheral nociceptors in normal and arthritic rat knee joints

The effects of the endogenous cannabinoid anandamide were studied on peripheral, polymodal nociceptors recorded from normal and chronically inflamed (Freund's adjuvant) knee joint afferents in rats anaesthetized with pentobarbitone. Anandamide (860 nmol) caused a rapid, short lasting excitation...

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Bibliografiske detaljer
Main Authors: Gauldie, S D, McQueen, D S, Pertwee, R, Chessell, I P
Format: Artigo
Sprog:Inglês
Udgivet: 2001
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1572613/
https://ncbi.nlm.nih.gov/pubmed/11159713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0703890
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