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Adenosine A(1) receptor-mediated excitation of nociceptive afferents innervating the normal and arthritic rat knee joint

1. We tested the hypothesis that adenosine excites nociceptive primary afferents innervating the knee joint. 2. Neuronal recordings were made from fine nerve filaments innervating the knee joint in rats anaesthetized with pentobarbitone. Drugs were injected close-arterially (i.a.) or into the articu...

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Detalhes bibliográficos
Main Authors: Dowd, E, McQueen, D S, Chessell, I P, Humphrey, P P A
Formato: Artigo
Idioma:Inglês
Publicado em: 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1565696/
https://ncbi.nlm.nih.gov/pubmed/9863656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0702185
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