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β(1)-Adrenoceptors compensate for β(3)-adrenoceptors in ileum from β(3)-adrenoceptor knock-out mice

1. This study examines β(1)-, β(2)- and β(3)-adrenoceptor (AR)-mediated responses, mRNA levels and radioligand binding in ileum from β(3)-AR knock-out (−/−) (KO) and wild type (+/+) (FVB) mice. 2. In KO and FVB mice, SR59230A (100 nM) (β(3)-AR antagonist) antagonized responses to (−)-isoprenaline in...

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Bibliographic Details
Main Authors: Hutchinson, Dana S, Evans, Bronwyn A, Summers, Roger J
Format: Artigo
Language:Inglês
Published: 2001
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1572575/
https://ncbi.nlm.nih.gov/pubmed/11159692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0703828
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