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Characterization of β-adrenoceptor mediated smooth muscle relaxation and the detection of mRNA for β(1)-, β(2)- and β(3)-adrenoceptors in rat ileum

1. Functional and molecular approaches were used to characterize the β-AR subtypes mediating relaxation of rat ileal smooth muscle. 2. In functional studies, (−)-isoprenaline relaxation was unchanged by CGP20712A (β(1)-AR antagonist) or ICI118551 (β(2)-AR antagonist) but shifted by propranolol (pK(B...

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Detalhes bibliográficos
Main Authors: Roberts, S J, Papaioannou, M, Evans, B A, Summers, R J
Formato: Artigo
Idioma:Inglês
Publicado em: 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1566085/
https://ncbi.nlm.nih.gov/pubmed/10433503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0702605
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