Characterization of a novel mechanism accounting for the adverse cholinergic effects of the anticancer drug irinotecan

1. This study investigates the mechanisms accounting for the adverse cholinergic effects of the antitumour drug irinotecan. The activity of irinotecan and its active metabolite, 7-ethyl-10-hydroxy-camptothecin (SN-38), was assayed in models suitable for pharmacological studies on cholinergic system....

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Bibliografski detalji
Glavni autori: Blandizzi, Corrado, De Paolis, Barbara, Colucci, Rocchina, Lazzeri, Gloria, Baschiera, Fabio, Del Tacca, Mario
Format: Artigo
Jezik:Inglês
Izdano: 2001
Teme:
Papers
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1572526/
https://ncbi.nlm.nih.gov/pubmed/11156563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0703766
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