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Mechanism of action of the hypnotic zolpidem in vivo
Zolpidem is a widely used hypnotic agent acting at the GABA(A) receptor benzodiazepine site. On recombinant receptors, zolpidem displays a high affinity to α1-GABA(A) receptors, an intermediate affinity to α(2)- and α(3)-GABA(A) receptors and fails to bind to α(5)-GABA(A) receptors. However, it is n...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2000
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1572473/ https://ncbi.nlm.nih.gov/pubmed/11090095 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0703717 |
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