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Effect of saikosaponin, a triterpene saponin, on apoptosis in lymphocytes: association with c-myc, p53, and bcl-2 mRNA
1. The mechanisms involved in the apoptotic effect of saikosaponin-d, a triterpene saponin from Bupleurum falcatum L., were studied in human CEM lymphocytes and compared with those of dexamethasone (3×10(−7) M). 2. Saikosaponin-d (10(−8) to 10(−5) M) inhibited the serum-stimulated [(3)H]-thymidine i...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2000
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1572450/ https://ncbi.nlm.nih.gov/pubmed/11090099 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0703559 |
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