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Effect of saikosaponin, a triterpene saponin, on apoptosis in lymphocytes: association with c-myc, p53, and bcl-2 mRNA

1. The mechanisms involved in the apoptotic effect of saikosaponin-d, a triterpene saponin from Bupleurum falcatum L., were studied in human CEM lymphocytes and compared with those of dexamethasone (3×10(−7) M). 2. Saikosaponin-d (10(−8) to 10(−5) M) inhibited the serum-stimulated [(3)H]-thymidine i...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Hsu, Ming-Jen, Cheng, Jur-Shan, Huang, Huei-Chen
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group 2000
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC1572450/
https://ncbi.nlm.nih.gov/pubmed/11090099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0703559
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