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Effect of endothelin antagonists, including the novel ET(A) receptor antagonist LBL 031, on endothelin-1 and lipopolysaccharide-induced microvascular leakage in rat airways

1. The effect of the novel ET(A) receptor antagonist LBL 031 and other selective and mixed endothelin receptor antagonists on endothelin-1 (ET-1)-induced and lipopolysaccharide (LPS)-induced microvascular leakage was assessed in rat airways. 2. Intravenously administered ET-1 (1 nmole kg(−1)) or LPS...

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Detalhes bibliográficos
Main Authors: Hele, Dave J, Birrell, Mark A, Webber, Stephen E, Foster, Martyn L, Belvisi, Maria G
Formato: Artigo
Idioma:Inglês
Publicado em: 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1572444/
https://ncbi.nlm.nih.gov/pubmed/11082120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0703691
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