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Endothelial nitric oxide synthase is a site of superoxide synthesis in endothelial cells treated with glyceryl trinitrate
1. Tolerance to glyceryl trinitrate (GTN) involves superoxide (O(2)(.−)) production by endothelial cells. Nitric oxide synthase (NOS) produces O(2)(.−) when L-arginine (L-arg) is limited. The purpose of this study was to test the hypothesis that GTN stimulates NOS to increase O(2)(.−) synthesis in e...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2000
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1572421/ https://ncbi.nlm.nih.gov/pubmed/11053225 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0703665 |
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