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Extracellular signal-regulated kinase 1/2 control Ca(2+)-independent force development in histamine-stimulated bovine tracheal smooth muscle

1. The role of extracellular signal-regulated kinase (ERK)-1 and ERK-2 in controlling histamine-induced tone in bovine trachealis was investigated. PD 098059, an inhibitor of mitogen-activated protein kinase kinase (MKK)-1, had no effect on the histamine concentration-response relationship that desc...

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Autors principals: Koch, Andrea, Nasuhara, Yasuyuki, Barnes, Peter J, Lindsay, Mark A, Giembycz, Mark A
Format: Artigo
Idioma:Inglês
Publicat: 2000
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1572419/
https://ncbi.nlm.nih.gov/pubmed/11053220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0703663
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