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Inhibition of acetylcholine muscarinic M(1) receptor function by the M(1)-selective ligand muscarinic toxin 7 (MT-7)

1. MT-7 (1–30 nM), a peptide toxin isolated from the venom of the green mamba Dendroaspis angusticeps and previously found to bind selectively to the muscarinic M(1) receptor, inhibited the acetylcholine (ACh)-stimulated [(35)S]-guanosine-5′-O-(3-thio)triphosphate ([(35)S]-GTPγS) binding to membrane...

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Détails bibliographiques
Auteurs principaux: Olianas, Maria C, Maullu, Carlo, Adem, Abdu, Mulugeta, Ezra, Karlsson, Evert, Onali, Pierluigi
Format: Artigo
Langue:Inglês
Publié: 2000
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1572361/
https://ncbi.nlm.nih.gov/pubmed/11015294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0703606
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