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Inhibition of acetylcholine muscarinic M(1) receptor function by the M(1)-selective ligand muscarinic toxin 7 (MT-7)
1. MT-7 (1–30 nM), a peptide toxin isolated from the venom of the green mamba Dendroaspis angusticeps and previously found to bind selectively to the muscarinic M(1) receptor, inhibited the acetylcholine (ACh)-stimulated [(35)S]-guanosine-5′-O-(3-thio)triphosphate ([(35)S]-GTPγS) binding to membrane...
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| Auteurs principaux: | , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2000
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1572361/ https://ncbi.nlm.nih.gov/pubmed/11015294 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0703606 |
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