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Effects of clozapine on rat striatal muscarinic receptors coupled to inhibition of adenylyl cyclase activity and on the human cloned m4 receptor

1. Clozapine has recently been claimed to behave as a selective and full agonist at the cloned m4 muscarinic receptor artificially expressed in Chinese hamster ovary (CHO) cells. In the present study we have investigated whether clozapine could activate the rat striatal muscarinic receptors coupled...

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Detalhes bibliográficos
Main Authors: Olianas, Maria C, Maullu, Carlo, Onali, Pierluigi
Formato: Artigo
Idioma:Inglês
Publicado em: 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1564946/
https://ncbi.nlm.nih.gov/pubmed/9351494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0701357
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