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The effect of Gi-protein inactivation on basal, and β(1)- and β(2)AR-stimulated contraction of myocytes from transgenic mice overexpressing the β(2)-adrenoceptor

1. The atria and ventricles of transgenic mice (TGβ(2)) with cardiac overexpression of the human β(2)-adrenoceptor (β(2)AR) were initially reported to show maximum contractility in the absence of β-AR stimulation. However, we have previously observed a different phenotype in these mice, with myocyte...

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Detalhes bibliográficos
Main Authors: Gong, Haibin, Adamson, Dawn L, Ranu, Hardeep K, Koch, Walter J, Heubach, Jürgen F, Ravens, Ursula, Zolk, Oliver, Harding, Sian E
Formato: Artigo
Idioma:Inglês
Publicado em: 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1572349/
https://ncbi.nlm.nih.gov/pubmed/11015312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0703591
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