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Overexpression of β(1)-adrenoceptors in adult rat ventricular myocytes enhances CGP 12177A cardiostimulation: implications for ‘putative' β(4)-adrenoceptor pharmacology

1. CGP 12177A mediates cardiostimulation by activation of the ‘putative' β(4)-adrenoceptor; however, it has recently been reported that disruption of the β(1)-adrenoceptor gene abolishes this effect. We have adenovirally overexpressed β(1)-adrenoceptors in isolated, cultured adult rat ventricul...

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Détails bibliographiques
Auteurs principaux: Lewis, Clive J, Gong, Haibin, Brown, Morris J, Harding, Sian E
Format: Artigo
Langue:Inglês
Publié: 2004
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1574257/
https://ncbi.nlm.nih.gov/pubmed/14757703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0705668
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