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Endotoxin causes up-regulation of endothelin receptors in cultured hepatic stellate cells via nitric oxide-dependent and -independent mechanisms

1. Hepatic stellate cells (HSC) and their transformed phenotype found in the chronically injured liver play important roles in hepatic physiology and pathology. HSC produce and react to a potent contractile peptide endothelin-1 (ET-1) and also synthesize a vasorelaxant nitric oxide (NO) upon stimula...

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Autores principales: Gandhi, Chandrashekhar R, Uemura, Tadahiro, Kuddus, Ruhul
Formato: Artigo
Lenguaje:Inglês
Publicado: 2000
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1572329/
https://ncbi.nlm.nih.gov/pubmed/10991926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0703577
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