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Induction of COX-2 and PGE(2) biosynthesis by IL-1β is mediated by PKC and mitogen-activated protein kinases in murine astrocytes
1. Interleukin-1 (IL-1) is an important mediator of immunoinflammatory responses in the brain. In the present study, we examined whether prostaglandin E(2) (PGE(2)) production after IL-1β stimulation is dependent upon activation of protein kinases in astroglial cells. 2. Astrocyte cultures stimulate...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2000
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1572306/ https://ncbi.nlm.nih.gov/pubmed/10960082 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0703557 |
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