Induction of COX-2 and PGE(2) biosynthesis by IL-1β is mediated by PKC and mitogen-activated protein kinases in murine astrocytes

1. Interleukin-1 (IL-1) is an important mediator of immunoinflammatory responses in the brain. In the present study, we examined whether prostaglandin E(2) (PGE(2)) production after IL-1β stimulation is dependent upon activation of protein kinases in astroglial cells. 2. Astrocyte cultures stimulate...

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Main Authors: Molina-Holgado, Eduardo, Ortiz, Sergio, Molina-Holgado, Francisco, Guaza, Carmen
Format: Artigo
Jezik:Inglês
Izdano: 2000
Teme:
Papers
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1572306/
https://ncbi.nlm.nih.gov/pubmed/10960082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0703557
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