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Cytochrome P450 mono-oxygenase gene expression and protein activity in cultures of adult cardiomyocytes of the rat

1. There are a substantial number of drugs acting either directly or indirectly on the heart, but surprisingly, little is known about the metabolic capacity of heart muscle cells. 2. We therefore investigated the gene expression and protein activity of cytochrome P450 isozymes in cultures of adult c...

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Autors principals: Thum, Thomas, Borlak, Jürgen
Format: Artigo
Idioma:Inglês
Publicat: 2000
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1572248/
https://ncbi.nlm.nih.gov/pubmed/10952662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0703465
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