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Nitroparacetamol exhibits anti-inflammatory and anti-nociceptive activity
Nitroparacetamol (NCX-701) is a newly synthesized nitric oxide-releasing derivative of paracetamol. Following i.p. administration, nitroparacetamol inhibits carrageenan-induced hindpaw oedema formation (ED(50), 169.4 μmol kg(−1)) and mechanical hyperalgesia (ED(50), 156 μmol kg(−1)) in the rat. In c...
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| Autors principals: | , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2000
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1572245/ https://ncbi.nlm.nih.gov/pubmed/10928944 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0703509 |
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