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Novel proline endopeptidase inhibitors do not modify Aβ40/42 formation and degradation by human cells expressing wild-type and Swedish mutated β-amyloid precursor protein

1. Previous studies have suggested that proline endopeptidase (PE) could participate to the catabolism of the β-amyloid peptide (Aβ) or to the physiopathological maturation of the β-amyloid protein precursor (βAPP). We have examined the putative ability of human purified PE to catabolize Aβ40 and Aβ...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Petit, Agnès, Barelli, Hélène, Morain, Philippe, Checler, Frédéric
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2000
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC1572208/
https://ncbi.nlm.nih.gov/pubmed/10928965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0703440
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