Voltage-dependent blockade of normal and mutant muscle sodium channels by benzylalcohol

1. We studied the effects of benzylalcohol on heterologously expressed wild type (WT), paramyotonia congenita (R1448H) and hyperkalaemic periodic paralysis (M1360V) mutant α-subunits of human skeletal muscle sodium channels. 2. Benzylalcohol blocked rested channels at −150 mV membrane potential, wit...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Haeseler, G, Mamarvar, M, Bufler, J, Dengler, R, Hecker, H, Aronson, J K, Piepenbrock, S, Leuwer, M
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2000
Gaiak:
Papers
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1572205/
https://ncbi.nlm.nih.gov/pubmed/10903972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0703447
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