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Betaxolol, a β(1)-adrenoceptor antagonist, reduces Na(+) influx into cortical synaptosomes by direct interaction with Na(+) channels: comparison with other β-adrenoceptor antagonists
1. Betaxolol, a β(1)-adrenoceptor antagonist used for the treatment of glaucoma, is known to be neuroprotective in paradigms of ischaemia/excitotoxicity. In this study, we examined whether betaxolol and other β-adrenoceptor antagonists interact directly with neurotoxin binding to sites 1 and 2 of th...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2000
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1572129/ https://ncbi.nlm.nih.gov/pubmed/10864881 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0703369 |
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