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Caspase inhibition and limitation of myocardial infarct size: protection against lethal reperfusion injury
Ischaemia-reperfusion injury causes cell death by both necrosis and apoptosis. Caspase activation is a major event in apoptosis. We therefore examined the effect of caspase inhibitors during reperfusion upon myocardial infarction. Rat isolated hearts were subjected to 35 min coronary occlusion and 1...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2000
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1572087/ https://ncbi.nlm.nih.gov/pubmed/10807653 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0703336 |
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