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Caspase inhibition and limitation of myocardial infarct size: protection against lethal reperfusion injury

Ischaemia-reperfusion injury causes cell death by both necrosis and apoptosis. Caspase activation is a major event in apoptosis. We therefore examined the effect of caspase inhibitors during reperfusion upon myocardial infarction. Rat isolated hearts were subjected to 35 min coronary occlusion and 1...

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Detaylı Bibliyografya
Asıl Yazarlar: Mocanu, M M, Baxter, G F, Yellon, D M
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2000
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1572087/
https://ncbi.nlm.nih.gov/pubmed/10807653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0703336
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