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Peroxynitrite-mediated release of arachidonic acid from PC12 cells

A short term exposure of PC12 cells to a concentration of tert-butylhydroperoxide (tB-OOH) causing peroxynitrite-dependent DNA damage and cytotoxiticity promoted a release of arachidonic acid (AA) that was sensitive to phospholipase A(2) (PLA(2)) inhibitors and insensitive to phospholipase C or diac...

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Bibliografiske detaljer
Main Authors: Guidarelli, Andrea, Palomba, Letizia, Cantoni, Orazio
Format: Artigo
Sprog:Inglês
Udgivet: 2000
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1572026/
https://ncbi.nlm.nih.gov/pubmed/10780956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0703275
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