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Selective block of late Na(+) current by local anaesthetics in rat large sensory neurones
1. The actions of lignocaine and benzocaine on transient and late Na(+) current generated by large diameter (⩾50 μm) adult rat dorsal root ganglion neurones, were studied using patch-clamp techniques. 2. Both drugs blocked whole-cell late Na(+) current in a concentration-dependent manner. At 200 ms...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2000
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1572015/ https://ncbi.nlm.nih.gov/pubmed/10780966 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0703261 |
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