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Enhanced blood pressure sensitivity to DOCA-salt treatment in endothelin ET(B) receptor-deficient rats

The role of endothelin ET(B) receptor-mediated action in the development and maintenance of deoxycorticosterone acetate (DOCA)-salt-induced hypertension was evaluated using the spotting-lethal (sl) rat which carries a naturally occurring deletion in the ET(B) receptor gene. Homozygous (sl/sl) rats t...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Matsumura, Yasuo, Kuro, Toshihiko, Konishi, Fumiko, Takaoka, Masanori, Gariepy, Cheryl E, Yanagisawa, Masashi
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2000
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1571939/
https://ncbi.nlm.nih.gov/pubmed/10725252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0703157
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