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Bioactive β-bend structures for the antagonist hα CGRP(8–37) at the CGRP(1) receptor of the rat pulmonary artery

1. The aim of this study was to determine β-bend structures and the role of the N- and C-terminus in the antagonist hα CGRP(8–37) at the rat pulmonary artery CGRP receptor mediating hα CGRP relaxation. 2. Hα CGRP(8–37) Pro(16) (10(−6) M), with a bend-biasing residue (proline) at position 16, did not...

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Autores principales: Wisskirchen, F M, Doyle, P M, Gough, S L, Harris, C J, Marshall, I
Formato: Artigo
Lenguaje:Inglês
Publicado: 2000
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1571929/
https://ncbi.nlm.nih.gov/pubmed/10696108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0703152
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