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Conformational restraints revealing bioactive β-bend structures for hα CGRP(8–37) at the CGRP(2) receptor of the rat prostatic vas deferens

1. The main aim of this study was to identify putative β-bends and the role of the N- and C-terminus in the CGRP receptor antagonist hα CGRP(8–37), which was measured against hα CGRP inhibition of twitch responses in the rat prostatic vas deferens. 2. With a bend-biasing residue (proline) at positio...

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Detalhes bibliográficos
Main Authors: Wisskirchen, F M, Doyle, P M, Gough, S L, Harris, C J, Marshall, I
Formato: Artigo
Idioma:Inglês
Publicado em: 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1565896/
https://ncbi.nlm.nih.gov/pubmed/10205004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0702432
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