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The group II metabotropic glutamate receptor agonist, DCG-IV, alleviates akinesia following intranigral or intraventricular administration in the reserpine-treated rat

1. This study examined whether activation of group II metabotropic glutamate (mGlu) receptors in the substantia nigra pars reticulata (SNr) could reverse akinesia in a rodent model of Parkinson's disease (PD). 2. Male Sprague Dawley rats, stereotaxically cannulated above either the SNr or third...

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Detalhes bibliográficos
Main Authors: Dawson, Lee, Chadha, Anita, Megalou, Maria, Duty, Susan
Formato: Artigo
Idioma:Inglês
Publicado em: 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1571875/
https://ncbi.nlm.nih.gov/pubmed/10711353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0703105
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