A novel anti-diabetic drug, miglitol, markedly reduces myocardial infarct size in rabbits

1. We examined whether N-hydroxyethyl-1-deoxynojirimycin (miglitol), a new human anti-diabetic drug with effects to inhibit α-1,6-glucosidase glycogen debranching enzyme and reduce the glycogenolytic rate as well as to inhibit α-1,4-glucosidase, could reduce infarct size in the rabbit heart. Rabbits...

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Bibliografiske detaljer
Main Authors: Minatoguchi, Shinya, Arai, Masazumi, Uno, Yoshihiro, Kariya, Tatsuya, Nishida, Yoshio, Hashimoto, Kazuaki, Kawasaki, Masanori, Takemura, Genzou, Fujiwara, Takako, Fujiwara, Hisayoshi
Format: Artigo
Sprog:Inglês
Udgivet: 1999
Fag:
Papers
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1571807/
https://ncbi.nlm.nih.gov/pubmed/10588921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0702970
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