Selective cyclo-oxygenase-2 inhibitors aggravate ischaemia-reperfusion injury in the rat stomach

1. Effects of indomethacin, the selective cyclo-oxygenase (COX)-2 inhibitors NS-398 and DFU, and dexamethasone on gastric damage induced by 30 min ischaemia followed by 60 min reperfusion (I-R) were investigated in rats. Modulation of gastric levels of COX-1 and COX-2 mRNA by I-R was evaluated using...

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Bibliografiska uppgifter
Huvudupphovsmän: Maricic, Nenad, Ehrlich, Karlheinz, Gretzer, Britta, Schuligoi, Rufina, Respondek, Michael, Peskar, Brigitta M
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1999
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Papers
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1571805/
https://ncbi.nlm.nih.gov/pubmed/10588920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0702966
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