Disturbance of peristalsis in the guinea-pig isolated small intestine by indomethacin, but not cyclo-oxygenase isoform-selective inhibitors

1. Since the cyclo-oxygenase (COX) isoform-nonselective inhibitor indomethacin is known to modify intestinal motility, we analysed the effects of COX-1 and COX-2 inhibition on intestinal peristalsis. 2. Peristalsis in isolated segments of the guinea-pig small intestine was triggered by a rise of the...

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Detalhes bibliográficos
Main Authors: Shahbazian, Anaid, Schuligoi, Rufina, Heinemann, Akos, Peskar, Bernhard A, Holzer, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: 2001
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Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1572673/
https://ncbi.nlm.nih.gov/pubmed/11250881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0703940
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