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Inhibition of nuclear factor kappa B and induction of apoptosis in T-lymphocytes by sulfasalazine

1. Chronic inflammatory diseases have been shown to be associated with NF-κB activation and impaired apoptosis of immune cells. The aim of the present study was to investigate if sulfasalazine and its colonic metabolites 5-aminosalicylic acid (5ASA) and sulfapyridine affect NF-κB/Rel activation and...

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Detalhes bibliográficos
Main Authors: Liptay, Susanne, Bachem, Max, Häcker, Georg, Adler, Guido, Debatin, Klaus M, Schmid, Roland M
Formato: Artigo
Idioma:Inglês
Publicado em: 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1571782/
https://ncbi.nlm.nih.gov/pubmed/10602313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0702937
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