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Sulfasalazine: a potent and specific inhibitor of nuclear factor kappa B.
Transcription factors of the NF-kappaB/Rel family are critical for inducible expression of multiple genes involved in inflammatory responses. Sulfasalazine and its salicylate moiety 5-aminosalicylic acid are among the most effective agents for treating inflammatory bowel disease and rheumatoid arthr...
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| Udgivet i: | J Clin Invest |
|---|---|
| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Clinical Investigation
1998
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC508669/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9486988/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI992 |
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