Cardioprotective effects of N-hydroxyguanidine PR5 in myocardial ischaemia and reperfusion in rats

1. The potential for the N-hydroxyguanidine compound PR5 (N-(3,4-dimethoxy-2-chlorobenzylideneamino)-N′-hydroxyguanidine) as a cardioprotective agent in heart ischaemia and reperfusion injury was investigated using rat models. 2. Administration of 1–10 mg kg(−1) of PR5 5 min before 10 min of left co...

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Detaylı Bibliyografya
Asıl Yazarlar: Veveris, Maris, Dambrova, Maija, Cirule, Helena, Meirena, Dainuvite, Kalvinsh, Ivars, Wikberg, Jarl E S
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 1999
Konular:
Papers
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1571728/
https://ncbi.nlm.nih.gov/pubmed/10556947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0702887
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