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Cardioprotective effects of N-hydroxyguanidine PR5 in myocardial ischaemia and reperfusion in rats
1. The potential for the N-hydroxyguanidine compound PR5 (N-(3,4-dimethoxy-2-chlorobenzylideneamino)-N′-hydroxyguanidine) as a cardioprotective agent in heart ischaemia and reperfusion injury was investigated using rat models. 2. Administration of 1–10 mg kg(−1) of PR5 5 min before 10 min of left co...
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| Principais autores: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
1999
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1571728/ https://ncbi.nlm.nih.gov/pubmed/10556947 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0702887 |
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