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The Pseudomonas aeruginosa quorum-sensing signal molecule, N-(3-oxododecanoyl)-L-homoserine lactone, inhibits porcine arterial smooth muscle contraction

The Pseudomonas aeruginosa quorum sensing molecule N-(3-oxododecanoyl)-L-homoserine lactone (OdDHL) has been shown to suppress cytokine production in macrophages. We have examined the effect of OdDHL and related compounds on constrictor tone of porcine blood vessels. OdDHL (1–30 μM) caused a concent...

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Autors principals: Lawrence, R N, Dunn, W R, Bycroft, B, Camara, M, Chhabra, S R, Williams, P, Wilson, V G
Format: Artigo
Idioma:Inglês
Publicat: 1999
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1571710/
https://ncbi.nlm.nih.gov/pubmed/10556916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0702870
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