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Endothelium-derived hyperpolarizing factor but not NO reduces smooth muscle Ca(2+) during acetylcholine-induced dilation of microvessels

1. We hypothesized that nitric oxide (NO) and the endothelium-dependent hyperpolarizing factor (EDHF) may dilate microvessels by different cellular mechanisms, namely Ca(2+)-desensitization versus decrease in intracellular free calcium. 2. Effects of acetylcholine (ACh) and the NO donors sodium nitr...

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Autors principals: Bolz, Steffen-Sebastian, de Wit, Cor, Pohl, Ulrich
Format: Artigo
Idioma:Inglês
Publicat: 1999
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1571612/
https://ncbi.nlm.nih.gov/pubmed/10498843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0702775
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