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Endothelium-dependent smooth muscle hyperpolarization: do gap junctions provide a unifying hypothesis?

An endothelium-derived hyperpolarizing factor (EDHF) that is distinct from nitric oxide (NO) and prostanoids has been widely hypothesized to hyperpolarize and relax vascular smooth muscle following stimulation of the endothelium by agonists. Candidates as diverse as K(+) ions, eicosanoids, hydrogen...

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Dettagli Bibliografici
Autore principale: Griffith, Tudor M
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2004
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1574270/
https://ncbi.nlm.nih.gov/pubmed/15028638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0705698
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