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Electroencephalographic effects of thiopentone and its enantiomers in the rat: correlation with drug tissue distribution
1. To better understand the pharmacology of the thiopentone enantiomers, we studied their quantitative electroencephalographic effects and their distribution into vital tissues. 2. Adult Wistar rats were infused with rac-, R- or S-thiopentone at 4 mg kg(−1)min(−1) until death ensued. The EEG signal...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
1999
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1571591/ https://ncbi.nlm.nih.gov/pubmed/10498838 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0702745 |
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