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Inhibition of inflammatory actions of aminobisphosphonates by dichloromethylene bisphosphonate, a non-aminobisphosphonate

1. When injected intraperitoneally into mice in doses larger than those used clinically, all the amino derivatives of bisphosphonates (aminoBPs) tested induce a variety of inflammatory reactions such as induction of histidine decarboxylase (HDC, the histamine-forming enzyme), hypertrophy of the sple...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Endo, Yasuo, Shibazaki, Masahiko, Yamaguchi, Kouji, Nakamura, Masanori, Kosugi, Hiroshi
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1999
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1571205/
https://ncbi.nlm.nih.gov/pubmed/10193770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0702367
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