Developmental mechanisms underlying polydactyly in the mouse mutant Doublefoot

The pre-axial polydactylous mouse mutant Doublefoot has 6–9 digits per limb but lacks anteroposterior polarity (there is no biphalangeal digit 1). It differs from other polydactylous mutants in showing normal Shh expression, but polarizing activity (shown by mouse-chick grafting experiments) and hed...

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Bibliographic Details
Main Authors: Crick, Alexandra P, Babbs, Christian, Brown, Jennifer M, Morriss-Kay, Gillian M
Format: Artigo
Language:Inglês
Published: Blackwell Science Inc 2003
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Reviews
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1571056/
https://ncbi.nlm.nih.gov/pubmed/12587916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1469-7580.2003.00132.x
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