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Developmental mechanisms underlying polydactyly in the mouse mutant Doublefoot

The pre-axial polydactylous mouse mutant Doublefoot has 6–9 digits per limb but lacks anteroposterior polarity (there is no biphalangeal digit 1). It differs from other polydactylous mutants in showing normal Shh expression, but polarizing activity (shown by mouse-chick grafting experiments) and hed...

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Bibliografische gegevens
Hoofdauteurs: Crick, Alexandra P, Babbs, Christian, Brown, Jennifer M, Morriss-Kay, Gillian M
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Blackwell Science Inc 2003
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1571056/
https://ncbi.nlm.nih.gov/pubmed/12587916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1469-7580.2003.00132.x
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