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Developmental mechanisms underlying polydactyly in the mouse mutant Doublefoot

The pre-axial polydactylous mouse mutant Doublefoot has 6–9 digits per limb but lacks anteroposterior polarity (there is no biphalangeal digit 1). It differs from other polydactylous mutants in showing normal Shh expression, but polarizing activity (shown by mouse-chick grafting experiments) and hed...

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Detalhes bibliográficos
Main Authors: Crick, Alexandra P, Babbs, Christian, Brown, Jennifer M, Morriss-Kay, Gillian M
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1571056/
https://ncbi.nlm.nih.gov/pubmed/12587916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1469-7580.2003.00132.x
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