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Developmental mechanisms underlying polydactyly in the mouse mutant Doublefoot
The pre-axial polydactylous mouse mutant Doublefoot has 6–9 digits per limb but lacks anteroposterior polarity (there is no biphalangeal digit 1). It differs from other polydactylous mutants in showing normal Shh expression, but polarizing activity (shown by mouse-chick grafting experiments) and hed...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Blackwell Science Inc
2003
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1571056/ https://ncbi.nlm.nih.gov/pubmed/12587916 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1469-7580.2003.00132.x |
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