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Developmental mechanisms underlying polydactyly in the mouse mutant Doublefoot

The pre-axial polydactylous mouse mutant Doublefoot has 6–9 digits per limb but lacks anteroposterior polarity (there is no biphalangeal digit 1). It differs from other polydactylous mutants in showing normal Shh expression, but polarizing activity (shown by mouse-chick grafting experiments) and hed...

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Hlavní autoři: Crick, Alexandra P, Babbs, Christian, Brown, Jennifer M, Morriss-Kay, Gillian M
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Science Inc 2003
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1571056/
https://ncbi.nlm.nih.gov/pubmed/12587916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1469-7580.2003.00132.x
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