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The 5-HT(4) receptor antagonist ML10375 inhibits the constitutive activity of human 5-HT(4(c)) receptor
Transient expression in COS-7 cells of the recombinant human 5-hydroxytryptamine (5-HT) h5-HT(4(c)) receptor isoform led to constitutive activity of the receptor. The 5-HT(4) receptor antagonist 2-(cis-3,5-dimethylpiperidino)ethyl 4-amino-5-chloro-2-methoxybenzoate (ML10375) at 1 μM completely aboli...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
1998
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1571008/ https://ncbi.nlm.nih.gov/pubmed/9831890 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0702163 |
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