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Targeted Molecular Therapy of the PI3K Pathway: Therapeutic Significance of PI3K Subunit Targeting in Colorectal Carcinoma
OBJECTIVE: The phosphatidylinositol 3-kinase (PI3K) pathway promotes cancer cell proliferation and survival. The authors determined the pattern of distribution of PI3K pathway components (ie, the p85α regulatory subunit, p110α catalytic subunit, Akt1, Akt2, and the tumor suppressor PTEN) in human co...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2006
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1570577/ https://ncbi.nlm.nih.gov/pubmed/16772787 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/01.sla.0000220040.66012.a9 |
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