PI3K/AKT ACTIVATION IS CRITICAL FOR EARLY HEPATIC REGENERATION AFTER PARTIAL HEPATECTOMY

Hepatic resection is associated with rapid proliferation and regeneration of the remnant liver. Phosphatidylinositol 3-kinase (PI3K), composed of a p85α regulatory and a p110α catalytic subunit, participates in multiple cellular processes, including cell growth and survival; however, the role of PI3...

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Hoofdauteurs: Jackson, Lindsey N., Larson, Shawn D., Silva, Scott R., Rychahou, Piotr G., Chen, L. Andy, Qiu, Suimin, Rajaraman, Srinivasan, Evers, B. Mark
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2008
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2427188/
https://ncbi.nlm.nih.gov/pubmed/18388186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00062.2008
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