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A novel function of DNA polymerase ζ regulated by PCNA

DNA polymerase ζ (Polζ) participates in translesion DNA synthesis and is involved in the generation of the majority of mutations induced by DNA damage. The mechanisms that license access of Polζ to the primer terminus and regulate the extent of its participation in genome replication are poorly unde...

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Detalhes bibliográficos
Main Authors: Northam, Matthew R, Garg, Parie, Baitin, Dmitri M, Burgers, Peter M J, Shcherbakova, Polina V
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1570441/
https://ncbi.nlm.nih.gov/pubmed/16957771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601320
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